dbGaP Study Accession: phs003125

NIH Institute/Center: NIGMS

RADx Data Program: RADx-UP

DOI: 10.60773/veb6-px50

Release Date: 02/21/2023

Study Description: In the US, COVID-19 unveiled a disproportionate health burden in low income and underserved segments of society. In Louisiana, some of the greatest health and economic consequences are evident in Black communities. Furthermore, despite the widespread availability of SARS-CoV-2 vaccines, approximately 30% of the US population reports that they will not get vaccinated, and Black citizens and those with lower socio-economic status are more likely to have vaccine hesitancy. Thus, there is an urgent need to address vaccine hesitancy within the context of the COVID-19 pandemic and the current testing environment. The Louisiana Clinical and Translational Science (LA CaTS) Center provides the essential infrastructure and key foundational support for biomedical research in the region and is uniquely positioned to lead a community-engaged research project to determine solutions to decrease vaccine hesitancy and improve testing rates in the most underserved populations. Faith-based organizations (churches, mosques, temples, etc.) are trusted sources of information, especially among Black communities, and may represent an opportunity to convey accurate, unbiased health information regarding COVID-19 vaccinations and testing to the community. Many Black churches have well-developed health ministries that integrate faith and health for their members and the communities they serve. This study used a mixed-methods study design to determine the effectiveness of training church health ministers to educate their congregations about the safety and efficacy of COVID-19 vaccines for decreasing vaccine hesitancy and improving testing knowledge in underserved Black communities. The study randomized 98 participants from five churches to an intervention group that received counseling from their health ministers on the benefits of getting vaccinated and tested, or to a delayed intervention control group. The effects of the intervention on the primary outcome, vaccine hesitancy measured by a questionnaire, were administered to both groups after three weeks. Following the three-week control period, the delayed intervention control group also received the intervention and again administered the questionnaire. The study then conducted focus groups among a sub-sample of participants to obtain more granular information on sources of vaccine hesitancy and for their vaccine-related decisions. The achievement of the study's goals significantly increased the understanding of vaccine hesitancy within Black urban communities in Louisiana. The results informed the development of targeted interventions to increase vaccine coverage in the large, underserved populations across the American South.

Updated Date: 02/21/2023

Principal Investigator: Kirwan, John P

Has Data Files: No

Study Domain: Community Outreach Programs; Pandemic Perceptions or Decision-Making; Social Determinants of Health; Testing Rate or Uptake; Vaccination Rate or Uptake; Virological Testing

Data Collection Method: Interview or Focus Group; Survey; Unspecified COVID Testing Device

Keywords: COVID Education

Study Design: Longitudinal Cohort

Multi-Center Study: No

Data Types: Clinical; Questionnaire or Survey

Study Start Date: 07/01/2021

Study End Date: 06/30/2022

Species: Human

Sample Size: 98

Study Population Focus: Adults; African Americans; Lower Socioeconomic Status (SES) Populations; Older Adults or Elderly; Racial or Ethnic Minorities; Underserved or Vulnerable Populations

Publication URL: https://pubmed.ncbi.nlm.nih.gov/36807397/

Acknowledgement Statement: This study was supported through funding, 3U54GM104940-06S4, for the National Institute of General Medical Sciences (NIGMS) as part of the RADx-UP program. Approved users should acknowledge the provision of data access by dbGaP for accession phs003125.v1.p1, and the NIH RADx Data Hub. Approved users should also acknowledge the specific version(s) of the dataset(s) obtained from the NIH RADx Data Hub.

Funding Opportunity Announcement (FOA) Number: PA-20-272

NIH Grant or Contract Number(s): 3U54GM104940-06S4

Consent/Data Use Limitations: General Research Use